hrp0084p1-86 | Growth Hormone | ESPE2015

The Growth Hormone Treatment Results in the Increase of Irisin Concentration in Plasma

Wikiera Beata , Pukajlo Katarzyna , Laczmanski Lukasz , Sloka Natalia , Basiak Aleksander , Noczynska Anna , Bolanowski Marek , Daroszewski Jacek

Background: Brown adipose tissue metabolism is of remarkable pathophysiological interest, because it could be a target for therapies for obesity and metabolic syndrome. Irisin (Ir), recently identified adipomyokine is essential in a white-to-brown fatty tissue transdifferentiation, and mediates some of the positive influences on metabolic disorders through increase of energy expenditure. The exact regulation of Ir secretion and action is unknown but positive associations of ci...

hrp0095p1-319 | Growth and Syndromes | ESPE2022

Analysis of trabecular bone score in girls with Turner syndrome

Wikiera Beata , Syrycka Joanna , Nocon-Bohusz Julita , Halupczok-Żyła Jowita , Jawiarczyk Aleksandra , Bolanowski Marek , Noczynska Anna

Introduction: Short stature is the most common symptom of Turner Syndrome (TS). The height below the 3rd percentile is an indication for recombinant human growth hormone (rhGH) treatment. TS is also associated with gonadal failure and increased risk of fracture. Spinal trabecular bone score (TBS) is a novel bone imaging tool that can offer better bone evaluation in TS.Aim: To evaluate TBS in TS, its association with rhGH...